Nanoparticle-based Endodontic Antimicrobial Photodynamic Therapy
نویسندگان
چکیده
منابع مشابه
Nanoparticle-based endodontic antimicrobial photodynamic therapy.
OBJECTIVE To study the in vitro effects of poly(lactic-co-glycolic acid) (PLGA) nanoparticles loaded with the photosensitizer methylene blue (MB) and light against Enterococcus faecalis (ATCC 29212). MATERIALS AND METHODS The uptake and distribution of nanoparticles in E. faecalis in suspension was investigated by transmission electron microscopy (TEM) after incubation with PLGA complexed wit...
متن کاملcan antimicrobial photodynamic therapy (apdt) enhance the endodontic treatment?
in order to achieve a long-lasting effect, one of the main goals in root canal treatment is to eliminate the endodontic bacteria. conventional chemomechanical debridement is considered as the basic treatment in root canal therapy, but adjunctive techniques such as antimicrobial photodynamic therapy (apdt) can also be helpful. the aim of this study was to evaluate reports in the scientific liter...
متن کاملPolymeric Nanoparticle-Based Photodynamic Therapy for Chronic Periodontitis in Vivo
Antimicrobial photodynamic therapy (aPDT) is increasingly being explored for treatment of periodontitis. Here, we investigated the effect of aPDT on human dental plaque bacteria in suspensions and biofilms in vitro using methylene blue (MB)-loaded poly(lactic-co-glycolic) (PLGA) nanoparticles (MB-NP) and red light at 660 nm. The effect of MB-NP-based aPDT was also evaluated in a clinical pilot ...
متن کاملAntimicrobial photodynamic therapy combined with conventional endodontic treatment to eliminate root canal biofilm infection.
BACKGROUND AND OBJECTIVE To compare the effectiveness of antimicrobial photodynamic therapy (PDT), standard endodontic treatment and the combined treatment to eliminate bacterial biofilms present in infected root canals. STUDY DESIGN/MATERIALS AND METHODS Ten single-rooted freshly extracted human teeth were inoculated with stable bioluminescent Gram-negative bacteria, Proteus mirabilis and Ps...
متن کاملPhotodynamic Inactivation of Endopathogenic Microbiota Using Curcumin- mediated Antimicrobial Photodynamic Therapy
Root canal disinfection is one of the main factors governing success of endodontic therapy. Antimicrobial photodynamic therapy (aPDT) is presented as a promising antimicrobial therapy that can eliminate microbiota present in infected root canal systems. In this study, a series of experiments investigated the effects of aPDT on cell viability and biofilm degradation ability of endopathogenic mic...
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ژورنال
عنوان ژورنال: Journal of Endodontics
سال: 2010
ISSN: 0099-2399
DOI: 10.1016/j.joen.2009.10.011